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Tetrandrine inhibits the proliferation of mesangial cells induced by enzymatically deglycosylated human IgA1 via IgA receptor/MAPK/NF-κB signaling pathway

Objective: Despite the use of renin-angiotensin system blockade and immunosuppressive drugs, including corticosteroids, the current treatment regimens for Immunoglobulins A nephropathy (IgAN) are severely limited. The proliferation of mesangial cell and deposition of deglycosylated human IgA1 immune...

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Detalles Bibliográficos
Autores principales: Xu, Wencheng, Song, Wanci, Chen, Shuhe, Jin, Shanshan, Xue, Xue, Min, Jinwen, Wang, Xiaoqin, You, Pengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308221/
https://www.ncbi.nlm.nih.gov/pubmed/37397485
http://dx.doi.org/10.3389/fphar.2023.1150829