Stable kinetochore‐microtubule attachment requires loop‐dependent Ndc80‐Ndc80 binding

During cell division, kinetochores link chromosomes to spindle microtubules. The Ndc80 complex, a crucial microtubule binder, populates each kinetochore with dozens of copies. Whether adjacent Ndc80 complexes cooperate to promote microtubule binding remains unclear. Here we demonstrate that the Ndc8...

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Detalles Bibliográficos
Autores principales: Polley, Soumitra, Müschenborn, Helen, Terbeck, Melina, De Antoni, Anna, Vetter, Ingrid R, Dogterom, Marileen, Musacchio, Andrea, Volkov, Vladimir A, Huis in 't Veld, Pim J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308368/
https://www.ncbi.nlm.nih.gov/pubmed/37203876
http://dx.doi.org/10.15252/embj.2022112504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308368/
https://www.ncbi.nlm.nih.gov/pubmed/37203876
http://dx.doi.org/10.15252/embj.2022112504

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