Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond

Peptide loading of MHC-I molecules plays a critical role in the T cell response to infections and tumors as well as to interactions with inhibitory receptors on natural killer (NK) cells. To facilitate and optimize peptide acquisition, vertebrates have evolved specialized chaperones to stabilize MHC...

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Detalles Bibliográficos
Autores principales: Margulies, David H., Jiang, Jiansheng, Ahmad, Javeed, Boyd, Lisa F., Natarajan, Kannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308438/
https://www.ncbi.nlm.nih.gov/pubmed/37398669
http://dx.doi.org/10.3389/fimmu.2023.1179846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308438/
https://www.ncbi.nlm.nih.gov/pubmed/37398669
http://dx.doi.org/10.3389/fimmu.2023.1179846

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