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A pH‑responsive hyaluronic acid nano‑vehicle co‑encapsulating doxorubicin and all‑trans retinoic acid for the inhibition of hepatic stellate cell‑induced tumor growth and metastasis
All-trans retinoic acid (ATRA) has been implicated in the differentiation of hepatic stellate cells (HSCs). In the present study, the liver-targeting hyaluronic acid micelles (ADHG) were prepared for co-delivery of ATRA and doxorubicin (DOX) to block the HSC-hepatoma interrelation. To simulate the t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308492/ https://www.ncbi.nlm.nih.gov/pubmed/37326031 http://dx.doi.org/10.3892/mmr.2023.13029 |