Route and antigen shape immunity to dmLT-adjuvanted vaccines to a greater extent than biochemical stress or formulation excipients

A key aspect to vaccine efficacy is formulation stability. Biochemical evaluations provide information on optimal compositions or thermal stability but are routinely validated by ex vivo analysis and not efficacy in animal models. Here we assessed formulations identified to improve or reduce stabili...

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Detalles Bibliográficos
Autores principales: Stone, Addison E., Rambaran, Saraswatie, Trinh, Ivy V., Estrada, Marcus, Jarand, Curtis W., Williams, Blake S., Murrell, Amelie E., Huerter, Chelsea M., Bai, William, Palani, Surya, Nakanishi, Yukihiro, Laird, Renee M., Poly, Frederic M., Reed, Wayne F., White, Jessica A., Norton, Elizabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308557/
https://www.ncbi.nlm.nih.gov/pubmed/36732163
http://dx.doi.org/10.1016/j.vaccine.2023.01.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308557/
https://www.ncbi.nlm.nih.gov/pubmed/36732163
http://dx.doi.org/10.1016/j.vaccine.2023.01.033

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