Synthesis of the Brivaracetam Employing Asymmetric Photocatalysis and Continuous Flow Conditions

[Image: see text] An original total synthesis of the antiepileptic drug brivaracetam (BRV) is reported. The key step in the synthesis consists of an enantioselective photochemical Giese addition, promoted by visible-light and the chiral bifunctional photocatalyst Δ-RhS. Continuous flow conditions we...

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Detalles Bibliográficos
Autores principales: Franco, Marcelo S., Silva, Rodrigo C., Rosa, Gabriel H. S., Flores, Lara M., de Oliveira, Kleber T., de Assis, Francisco F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308561/
https://www.ncbi.nlm.nih.gov/pubmed/37396260
http://dx.doi.org/10.1021/acsomega.3c02134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308561/
https://www.ncbi.nlm.nih.gov/pubmed/37396260
http://dx.doi.org/10.1021/acsomega.3c02134

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