Step-Economic Total Synthesis of Melosatin A from Eugenol

[Image: see text] An efficient and straightforward route toward the isatin-type natural product melosatin A is reported, employing a trisubstituted aniline as a key intermediate. The latter was synthesized in 4 steps and 60% overall yield from eugenol, through its regioselective nitration, sequentia...

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Detalles Bibliográficos
Autores principales: Bolivar Ávila, Santiago J., Ledesma, Gabriela N., Kaufman, Teodoro S., Testero, Sebastián A., Larghi, Enrique L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308592/
https://www.ncbi.nlm.nih.gov/pubmed/37396254
http://dx.doi.org/10.1021/acsomega.3c02722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308592/
https://www.ncbi.nlm.nih.gov/pubmed/37396254
http://dx.doi.org/10.1021/acsomega.3c02722

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