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Step-Economic Total Synthesis of Melosatin A from Eugenol
[Image: see text] An efficient and straightforward route toward the isatin-type natural product melosatin A is reported, employing a trisubstituted aniline as a key intermediate. The latter was synthesized in 4 steps and 60% overall yield from eugenol, through its regioselective nitration, sequentia...
Autores principales: | Bolivar Ávila, Santiago J., Ledesma, Gabriela N., Kaufman, Teodoro S., Testero, Sebastián A., Larghi, Enrique L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308592/ https://www.ncbi.nlm.nih.gov/pubmed/37396254 http://dx.doi.org/10.1021/acsomega.3c02722 |
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