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The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells

BACKGROUND: MicroRNAs are a group of small non-coding RNAs that are involved in development and diseases such as cancer. Previously, we demonstrated that miR-335 is crucial for preventing collagen type XI alpha 1 (COL11A1)-mediated epithelial ovarian cancer (EOC) progression and chemoresistance. Her...

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Detalles Bibliográficos
Autores principales: Wu, Yi-Hui, Huang, Yu-Fang, Wu, Pei-Ying, Chang, Tzu-Hao, Huang, Soon-Cen, Chou, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308652/
https://www.ncbi.nlm.nih.gov/pubmed/37386587
http://dx.doi.org/10.1186/s13048-023-01191-5