Looking ahead in early-phase trial design to improve the drug development process: examples in oncology

BACKGROUND: Clinical trial design must consider the specific resource constraints and overall goals of the drug development process (DDP); for example, in designing a phase I trial to evaluate the safety of a drug and recommend a dose for a subsequent phase II trial. Here, we focus on design conside...

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Detalles Bibliográficos
Autores principales: Vanderbeek, Alyssa M., Redd, Robert A., Ventz, Steffen, Trippa, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308797/
https://www.ncbi.nlm.nih.gov/pubmed/37386450
http://dx.doi.org/10.1186/s12874-023-01979-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308797/
https://www.ncbi.nlm.nih.gov/pubmed/37386450
http://dx.doi.org/10.1186/s12874-023-01979-5

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