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Targeted depletion of pks+ bacteria from a fecal microbiota using specific antibodies

The pks island is one of the most prevalent pathogenicity islands among the Escherichia coli strains that colonize the colon of colorectal carcinoma (CRC) patients. This pathogenic island encodes the production of a nonribosomal polyketide-peptide named colibactin, which induces double-strand breaks...

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Detalles Bibliográficos
Autores principales: Blanco-Míguez, Aitor, Marcos-Fernández, Raquel, Guadamuro-García, Lucía, Fdez-Riverola, Florentino, Cubiella, Joaquín, Lourenço, Anália, Margolles, Abelardo, Sánchez, Borja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308883/
https://www.ncbi.nlm.nih.gov/pubmed/37219498
http://dx.doi.org/10.1128/msystems.00079-23