Ex Vivo Infection of Human Skin Models with Herpes Simplex Virus 1: Accessibility of the Receptor Nectin-1 during Formation or Impairment of Epidermal Barriers Is Restricted by Tight Junctions

Herpes simplex virus 1 (HSV-1) must overcome epidermal barriers to reach its receptors on keratinocytes and initiate infection in human skin. The cell-adhesion molecule nectin-1, which is expressed in human epidermis, acts as an efficient receptor for HSV-1 but is not within reach of the virus upon...

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Detalles Bibliográficos
Autores principales: De La Cruz, Nydia C., Möckel, Maureen, Niehues, Hanna, Rübsam, Matthias, Malter, Wolfram, Zinser, Max, Krummenacher, Claude, Knebel-Mörsdorf, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308952/
https://www.ncbi.nlm.nih.gov/pubmed/37289055
http://dx.doi.org/10.1128/jvi.00262-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308952/
https://www.ncbi.nlm.nih.gov/pubmed/37289055
http://dx.doi.org/10.1128/jvi.00262-23

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