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Serotonin and dopamine depletion in distinct brain regions may cause anxiety in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice as a model of early Parkinson’s disease

In this study, we aimed to evaluate the association of early anxious behavior with serotonin, dopamine, and their metabolites in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) murine model of Parkinson’s disease. Forty C57BL/6 male mice were randomly divided into the control group (n = 20) an...

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Detalles Bibliográficos
Autores principales: Yang, Ruixi, Ye, Suzhen, Zhang, Shuping, Huang, Hanjin, Zhang, Yun, Yang, Yao, Xie, Shu, He, Lin, Yang, Yuwei, Shi, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309109/
https://www.ncbi.nlm.nih.gov/pubmed/37384936
http://dx.doi.org/10.1097/WNR.0000000000001922