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Collective endpoint of visual acuity and contrast sensitivity function from hierarchical Bayesian joint modeling

Clinical trials typically analyze multiple endpoints for signals of efficacy. To improve signal detection for treatment effects using the high-dimensional data collected in trials, we developed a hierarchical Bayesian joint model (HBJM) to compute a five-dimensional collective endpoint (CE(5D)) of c...

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Detalles Bibliográficos
Autores principales: Zhao, Yukai, Lesmes, Luis Andres, Dorr, Michael, Lu, Zhong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309166/
https://www.ncbi.nlm.nih.gov/pubmed/37378989
http://dx.doi.org/10.1167/jov.23.6.13