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Collective endpoint of visual acuity and contrast sensitivity function from hierarchical Bayesian joint modeling
Clinical trials typically analyze multiple endpoints for signals of efficacy. To improve signal detection for treatment effects using the high-dimensional data collected in trials, we developed a hierarchical Bayesian joint model (HBJM) to compute a five-dimensional collective endpoint (CE(5D)) of c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309166/ https://www.ncbi.nlm.nih.gov/pubmed/37378989 http://dx.doi.org/10.1167/jov.23.6.13 |