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Trained immunity as a potential target for therapeutic immunomodulation in Duchenne muscular dystrophy

Dysregulated inflammation involving innate immune cells, particularly of the monocyte/macrophage lineage, is a key contributor to the pathogenesis of Duchenne muscular dystrophy (DMD). Trained immunity is an evolutionarily ancient protective mechanism against infection, in which epigenetic and metab...

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Detalles Bibliográficos
Autores principales: Petrof, Basil J., Podolsky, Tom, Bhattarai, Salyan, Tan, Jiahui, Ding, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309206/
https://www.ncbi.nlm.nih.gov/pubmed/37398642
http://dx.doi.org/10.3389/fimmu.2023.1183066