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Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC

F-box and leucine-rich repeat protein 18 (FBXL18) is an E3 ubiquitin ligase that is reported to be involved in the tumorigenesis of various types of cancer. However, it remains unknown whether FBXL18 is correlated with hepatocarcinogenesis. METHODS AND RESULTS: In the current study, we found that FB...

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Detalles Bibliográficos
Autores principales: Yu, Hong-Qiang, Li, Feng, Xiong, HaoJun, Fang, Lei, Zhang, Jie, Bie, Ping, Xie, Chuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309527/
https://www.ncbi.nlm.nih.gov/pubmed/37378633
http://dx.doi.org/10.1097/HC9.0000000000000198