OptIC-Notch reveals mechanism that regulates receptor interactions with CSL

Active Notch signalling is elicited through receptor–ligand interactions that result in release of the Notch intracellular domain (NICD), which translocates into the nucleus. NICD activates transcription at target genes, forming a complex with the DNA-binding transcription factor CSL [CBF1/Su(H)/LAG...

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Detalles Bibliográficos
Autores principales: Townson, Jonathan M., Gomez-Lamarca, Maria J., Santa Cruz Mateos, Carmen, Bray, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309584/
https://www.ncbi.nlm.nih.gov/pubmed/37294169
http://dx.doi.org/10.1242/dev.201785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309584/
https://www.ncbi.nlm.nih.gov/pubmed/37294169
http://dx.doi.org/10.1242/dev.201785

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