Cargando…
OptIC-Notch reveals mechanism that regulates receptor interactions with CSL
Active Notch signalling is elicited through receptor–ligand interactions that result in release of the Notch intracellular domain (NICD), which translocates into the nucleus. NICD activates transcription at target genes, forming a complex with the DNA-binding transcription factor CSL [CBF1/Su(H)/LAG...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309584/ https://www.ncbi.nlm.nih.gov/pubmed/37294169 http://dx.doi.org/10.1242/dev.201785 |