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Myc promotes polyploidy in murine trophoblast cells and suppresses senescence
The placenta is essential for reproductive success. The murine placenta includes polyploid giant cells that are crucial for its function. Polyploidy occurs broadly in nature but its regulators and significance in the placenta are unknown. We have discovered that many murine placental cell types are...
Autores principales: | Singh, Vijay Pratap, Hassan, Huzaifa, Deng, Fengyan, Tsuchiya, Dai, McKinney, Sean, Ferro, Kevin, Gerton, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309589/ https://www.ncbi.nlm.nih.gov/pubmed/37278344 http://dx.doi.org/10.1242/dev.201581 |
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