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A human model of Buruli ulcer: The case for controlled human infection and considerations for selecting a Mycobacterium ulcerans challenge strain

Critical knowledge gaps regarding infection with Mycobacterium ulcerans, the cause of Buruli ulcer (BU), have impeded development of new therapeutic approaches and vaccines for prevention of this neglected tropical disease. Here, we review the current understanding of host–pathogen interactions and...

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Detalles Bibliográficos
Autores principales: Muhi, Stephen, Osowicki, Joshua, O’Brien, Daniel, Johnson, Paul D. R., Pidot, Sacha, Doerflinger, Marcel, Marshall, Julia L., Pellegrini, Marc, McCarthy, James, Stinear, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309606/
https://www.ncbi.nlm.nih.gov/pubmed/37384606
http://dx.doi.org/10.1371/journal.pntd.0011394