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A human model of Buruli ulcer: The case for controlled human infection and considerations for selecting a Mycobacterium ulcerans challenge strain
Critical knowledge gaps regarding infection with Mycobacterium ulcerans, the cause of Buruli ulcer (BU), have impeded development of new therapeutic approaches and vaccines for prevention of this neglected tropical disease. Here, we review the current understanding of host–pathogen interactions and...
Autores principales: | Muhi, Stephen, Osowicki, Joshua, O’Brien, Daniel, Johnson, Paul D. R., Pidot, Sacha, Doerflinger, Marcel, Marshall, Julia L., Pellegrini, Marc, McCarthy, James, Stinear, Timothy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309606/ https://www.ncbi.nlm.nih.gov/pubmed/37384606 http://dx.doi.org/10.1371/journal.pntd.0011394 |
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