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Lansoprazole protects hepatic cells against cisplatin-induced oxidative stress through the p38 MAPK/ARE/Nrf2 pathway

Lansoprazole, a proton pump inhibitor, can exert antioxidant effects through the induction of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, independently of the inhibition of acid secretion in the gastrointestinal tract. Lansoprazole has been reported to provide hepatoprotection in...

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Detalles Bibliográficos
Autores principales: Yamagishi, Naoko, Yamamoto, Yuta, Nishi, Toshio, Ito, Takao, Kanai, Yoshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309994/
https://www.ncbi.nlm.nih.gov/pubmed/37384717
http://dx.doi.org/10.1371/journal.pone.0287788