Accelerated absorption of regular insulin administered via a vascularizing permeable microchamber implanted subcutaneously in diabetic Rattus norvegicus

In Type 1 diabetes patients, even ultra-rapid acting insulins injected subcutaneously reach peak concentrations in 45 minutes or longer. The lag time between dosing and peak concentration, as well as intra- and inter-subject variability, render prandial glucose control and dose consistency difficult...

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Detalles Bibliográficos
Autores principales: Steyn, Leah V., Drew, Delaney, Vlachos, Demetri, Huey, Barry, Cocchi, Katie, Price, Nicholas D., Johnson, Robert, Putnam, Charles W., Papas, Klearchos K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310011/
https://www.ncbi.nlm.nih.gov/pubmed/37384782
http://dx.doi.org/10.1371/journal.pone.0278794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310011/
https://www.ncbi.nlm.nih.gov/pubmed/37384782
http://dx.doi.org/10.1371/journal.pone.0278794

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