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A high-throughput cigarette smoke-treated bronchosphere model for disease-relevant phenotypic compound screening

Cigarette smoking (CS) is the leading cause of COPD, and identifying the pathways that are driving pathogenesis in the airway due to CS exposure can aid in the discovery of novel therapies for COPD. An additional barrier to the identification of key pathways that are involved in the CS-induced patho...

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Detalles Bibliográficos
Autores principales: Beri, Pranjali, Woo, Young Jae, Schierenbeck, Katie, Chen, Kaisheng, Barnes, S. Whitney, Ross, Olivia, Krutil, Douglas, Quackenbush, Doug, Fang, Bin, Walker, John, Barnes, William, Toyama, Erin Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310037/
https://www.ncbi.nlm.nih.gov/pubmed/37384771
http://dx.doi.org/10.1371/journal.pone.0287809