Nicotinamide Riboside Improves Cardiac Function and Prolongs Survival After Disruption of the Cardiomyocyte Clock

The REV-ERB nuclear receptors are key components of the circadian clock. Loss of REV-ERBs in the mouse heart causes dilated cardiomyopathy and premature lethality. This is associated with a marked reduction in NAD(+) production, but whether this plays a role in the pathophysiology of this heart fail...

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Detalles Bibliográficos
Autores principales: Dierickx, Pieterjan, Carpenter, Bryce J., Celwyn, Isaac, Kelly, Daniel P., Baur, Joseph A., Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310318/
https://www.ncbi.nlm.nih.gov/pubmed/37389009
http://dx.doi.org/10.3389/fmmed.2022.887733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310318/
https://www.ncbi.nlm.nih.gov/pubmed/37389009
http://dx.doi.org/10.3389/fmmed.2022.887733

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