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Effect of Norovirus Inoculum Dose on Virus Kinetics, Shedding, and Symptoms

The effect of norovirus dose on outcomes such as virus shedding and symptoms after initial infection is not well understood. We performed a secondary analysis of a human challenge study by using Bayesian mixed-effects models. As the dose increased from 4.8 to 4,800 reverse transcription PCR units, t...

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Detalles Bibliográficos
Autores principales: Ge, Yang, Billings, W. Zane, Opekun, Antone, Estes, Mary, Graham, David, Leon, Juan, Koelle, Katia, Shen, Ye, Atmar, Robert, Lopman, Benjamin, Handel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310361/
https://www.ncbi.nlm.nih.gov/pubmed/37347494
http://dx.doi.org/10.3201/eid2907.230117