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Acute myeloid leukemia cells and MSC-derived exosomes inhibiting transformation in myelodysplastic syndrome

AIMS: To investigate the mechanism of exosomes' role in the transformation of MDS to AML. METHODS: Exosomes in culture supernatants of MDS and AML cell lines, were extracted by ultrafiltration and identified in three ways: morphology, size, and exosome protein surface markers. Exosomes from AML...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoli, Ren, Fanggang, Li, Shuo, Zhang, Na, Pu, Jeffrey J., Zhang, Hongyu, Xu, Zhifang, Tan, Yanhong, Chen, Xiuhua, Chang, Jianmei, Wang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310589/
https://www.ncbi.nlm.nih.gov/pubmed/37382733
http://dx.doi.org/10.1007/s12672-023-00714-2