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When push comes to shove - RNA polymerase and DNA-bound protein roadblocks

In recent years, transcriptional roadblocking has emerged as a crucial regulatory mechanism in gene expression, whereby other DNA-bound obstacles can block the progression of transcribing RNA polymerase (RNAP), leading to RNAP pausing and ultimately dissociation from the DNA template. In this review...

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Detalles Bibliográficos
Autores principales: Hao, Nan, Donnelly, Alana J., Dodd, Ian B., Shearwin, Keith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310618/
https://www.ncbi.nlm.nih.gov/pubmed/37396453
http://dx.doi.org/10.1007/s12551-023-01064-7