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Down-regulation of peptidylarginine deiminase type 1 in reconstructed human epidermis disturbs nucleophagy in the granular layer and affects barrier function

Deimination is a post-translational modification catalyzed by a family of enzymes named peptidylarginine deiminases (PADs). PADs transform arginine residues of protein substrates into citrulline. Deimination has been associated with numerous physiological and pathological processes. In human skin, t...

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Detalles Bibliográficos
Autores principales: Alioli, Adebayo Candide, Briot, Julie, Pons, Carole, Yang, Hang, Gairin, Marie, Goudounèche, Dominique, Cau, Laura, Simon, Michel, Méchin, Marie-Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310762/
https://www.ncbi.nlm.nih.gov/pubmed/37385992
http://dx.doi.org/10.1038/s41420-023-01509-8