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Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer’s disease (AD), and its accumulation has been considered as the molecular driver of Alzheimer’s pathogenesis and progression. Aβ has been the prime target for the development of AD therapy. However, the repeated failures o...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Chen, Huaqiu, Li, Ran, Sterling, Keenan, Song, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310781/
https://www.ncbi.nlm.nih.gov/pubmed/37386015
http://dx.doi.org/10.1038/s41392-023-01484-7