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Discovery of highly immunogenic spleen-resident FCGR3(+)CD103(+) cDC1s differentiated by IL-33-primed ST2(+) basophils
Recombinant interleukin-33 (IL-33) inhibits tumor growth, but the detailed immunological mechanism is still unknown. IL-33-mediated tumor suppression did not occur in Batf3(−/−) mice, indicating that conventional type 1 dendritic cells (cDC1s) play a key role in IL-33-mediated antitumor immunity. A...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310784/ https://www.ncbi.nlm.nih.gov/pubmed/37246159 http://dx.doi.org/10.1038/s41423-023-01035-8 |