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SMYD3 drives the proliferation in gastric cancer cells via reducing EMP1 expression in an H4K20me3-dependent manner

Protein lysine methyltransferase SET and MYND domain-containing 3 (SMYD3) is aberrantly expressed in various cancer settings. The mechanisms that SMYD3 activates the expression of critical pro-tumoral genes in an H3K4me3-dependent manner have been well described in previous reports. Besides H3K4me3,...

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Detalles Bibliográficos
Autores principales: Zeng, Yi, Ma, Gang, Cai, Fenglin, Wang, Pengliang, Liang, Han, Zhang, Rupeng, Deng, Jingyu, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310787/
https://www.ncbi.nlm.nih.gov/pubmed/37386026
http://dx.doi.org/10.1038/s41419-023-05907-9