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Single cell Hi-C identifies plastic chromosome conformations underlying the gastrulation enhancer landscape
Embryonic development involves massive proliferation and differentiation of cell lineages. This must be supported by chromosome replication and epigenetic reprogramming, but how proliferation and cell fate acquisition are balanced in this process is not well understood. Here we use single cell Hi-C...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310791/ https://www.ncbi.nlm.nih.gov/pubmed/37386027 http://dx.doi.org/10.1038/s41467-023-39549-4 |