Single cell Hi-C identifies plastic chromosome conformations underlying the gastrulation enhancer landscape

Embryonic development involves massive proliferation and differentiation of cell lineages. This must be supported by chromosome replication and epigenetic reprogramming, but how proliferation and cell fate acquisition are balanced in this process is not well understood. Here we use single cell Hi-C...

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Detalles Bibliográficos
Autores principales: Rappoport, Nimrod, Chomsky, Elad, Nagano, Takashi, Seibert, Charlie, Lubling, Yaniv, Baran, Yael, Lifshitz, Aviezer, Leung, Wing, Mukamel, Zohar, Shamir, Ron, Fraser, Peter, Tanay, Amos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310791/
https://www.ncbi.nlm.nih.gov/pubmed/37386027
http://dx.doi.org/10.1038/s41467-023-39549-4

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