The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells

Mast cells are central players in allergy and asthma, and their dysregulated responses lead to reduced quality of life and life-threatening conditions such as anaphylaxis. The RNA modification N(6)-methyladenosine (m(6)A) has a prominent impact on immune cell functions, but its role in mast cells re...

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Detalles Bibliográficos
Autores principales: Leoni, Cristina, Bataclan, Marian, Ito-Kureha, Taku, Heissmeyer, Vigo, Monticelli, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310798/
https://www.ncbi.nlm.nih.gov/pubmed/37386028
http://dx.doi.org/10.1038/s41467-023-39614-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310798/
https://www.ncbi.nlm.nih.gov/pubmed/37386028
http://dx.doi.org/10.1038/s41467-023-39614-y

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