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The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells
Mast cells are central players in allergy and asthma, and their dysregulated responses lead to reduced quality of life and life-threatening conditions such as anaphylaxis. The RNA modification N(6)-methyladenosine (m(6)A) has a prominent impact on immune cell functions, but its role in mast cells re...
Autores principales: | Leoni, Cristina, Bataclan, Marian, Ito-Kureha, Taku, Heissmeyer, Vigo, Monticelli, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310798/ https://www.ncbi.nlm.nih.gov/pubmed/37386028 http://dx.doi.org/10.1038/s41467-023-39614-y |
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