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Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice

Parallel to major changes in fatty acid and glucose metabolism, defect in branched-chain amino acid (BCAA) catabolism has also been recognized as a metabolic hallmark and potential therapeutic target for heart failure. However, BCAA catabolic enzymes are ubiquitously expressed in all cell types and...

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Detalles Bibliográficos
Autores principales: Yu, Jia-yu, Cao, Nancy, Rau, Christoph D., Lee, Ro-Po, Yang, Jieping, Flach, Rachel J. Roth, Petersen, Lauren, Zhu, Cansheng, Pak, Yea-Lyn, Miller, Russell A., Liu, Yunxia, Wang, Yibin, Li, Zhaoping, Sun, Haipeng, Gao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310802/
https://www.ncbi.nlm.nih.gov/pubmed/36991098
http://dx.doi.org/10.1038/s41401-023-01076-9