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Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice
Parallel to major changes in fatty acid and glucose metabolism, defect in branched-chain amino acid (BCAA) catabolism has also been recognized as a metabolic hallmark and potential therapeutic target for heart failure. However, BCAA catabolic enzymes are ubiquitously expressed in all cell types and...
Autores principales: | Yu, Jia-yu, Cao, Nancy, Rau, Christoph D., Lee, Ro-Po, Yang, Jieping, Flach, Rachel J. Roth, Petersen, Lauren, Zhu, Cansheng, Pak, Yea-Lyn, Miller, Russell A., Liu, Yunxia, Wang, Yibin, Li, Zhaoping, Sun, Haipeng, Gao, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310802/ https://www.ncbi.nlm.nih.gov/pubmed/36991098 http://dx.doi.org/10.1038/s41401-023-01076-9 |
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