Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors

Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main protease (Mp...

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Detalles Bibliográficos
Autores principales: Rampogu, Shailima, Jung, Tae Sung, Ha, Min Woo, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310815/
https://www.ncbi.nlm.nih.gov/pubmed/37386052
http://dx.doi.org/10.1038/s41598-023-36342-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310815/
https://www.ncbi.nlm.nih.gov/pubmed/37386052
http://dx.doi.org/10.1038/s41598-023-36342-7

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