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Repurposing and computational design of PARP inhibitors as SARS-CoV-2 inhibitors
Coronavirus disease 2019 (COVID-19) is a recent pandemic that caused serious global emergency. To identify new and effective therapeutics, we employed a drug repurposing approach. The poly (ADP ribose) polymerase inhibitors were used for this purpose and were repurposed against the main protease (Mp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310815/ https://www.ncbi.nlm.nih.gov/pubmed/37386052 http://dx.doi.org/10.1038/s41598-023-36342-7 |