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Mechanism of TNFα-induced downregulation of salt-inducible kinase 2 in adipocytes

Salt-inducible kinase 2 (SIK2) is highly expressed in white adipocytes, but downregulated in individuals with obesity and insulin resistance. These conditions are often associated with a low-grade inflammation in adipose tissue. We and others have previously shown that SIK2 is downregulated by tumor...

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Detalles Bibliográficos
Autores principales: Vaváková, Magdaléna, Hofwimmer, Kaisa, Laurencikiene, Jurga, Göransson, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310826/
https://www.ncbi.nlm.nih.gov/pubmed/37386070
http://dx.doi.org/10.1038/s41598-023-37340-5