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Chemoprevention of lotus leaf ethanolic extract through epigenetic activation of the NRF2-mediated pathway in murine skin JB6 P+ cell neoplastic transformation

BACKGROUND AND AIM: Skin is one barrier protecting from environmental risk factors that can make skin cells cancerous through DNA damage and oxidative stress. The nuclear factor erythroid 2-related factor 2 (NRF2) pathway is an anti-stress defense system that can be regulated by DNA methylation and...

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Detalles Bibliográficos
Autores principales: Tung, Yen-Chen, Sung, Ping-Hua, Chen, Pei-Chun, Wang, Hsiao Chi, Lee, Jong Hun, Su, Zheng-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310861/
https://www.ncbi.nlm.nih.gov/pubmed/37396151
http://dx.doi.org/10.1016/j.jtcme.2023.02.002