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Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells

BACKGROUND: Free fatty acid-induced lipotoxicity is considered to play an important role in pancreatic β-cell dysfunction. The effect of ginsenosides on palmitic acid-induced pancreatic beta-cells cell death and failure of glucose-stimulated secretion of insulin (GSIS) was evaluated in this study. M...

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Detalles Bibliográficos
Autores principales: Lee, Dahae, Choi, Sungyoul, Kang, Ki Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310875/
https://www.ncbi.nlm.nih.gov/pubmed/37397416
http://dx.doi.org/10.1016/j.jgr.2023.02.001