Cargando…
Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells
BACKGROUND: Free fatty acid-induced lipotoxicity is considered to play an important role in pancreatic β-cell dysfunction. The effect of ginsenosides on palmitic acid-induced pancreatic beta-cells cell death and failure of glucose-stimulated secretion of insulin (GSIS) was evaluated in this study. M...
Autores principales: | Lee, Dahae, Choi, Sungyoul, Kang, Ki Sung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310875/ https://www.ncbi.nlm.nih.gov/pubmed/37397416 http://dx.doi.org/10.1016/j.jgr.2023.02.001 |
Ejemplares similares
-
Baicalein protects rat insulinoma INS-1 cells from palmitate-induced lipotoxicity by inducing HO-1
por: Kwak, Hyun Jeong, et al.
Publicado: (2017) -
Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids
por: Urso, C.J., et al.
Publicado: (2021) -
Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets
por: Ciregia, Federica, et al.
Publicado: (2017) -
Tranilast protects pancreatic β-cells from palmitic acid-induced lipotoxicity via FoxO-1 inhibition
por: Choi, Hye-Eun, et al.
Publicado: (2023) -
Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity
por: Lytrivi, Maria, et al.
Publicado: (2020)