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Mesenchymal stem cell-derived exosome alleviates sepsis- associated acute liver injury by suppressing MALAT1 through microRNA-26a-5p: an innovative immunopharmacological intervention and therapeutic approach for sepsis

BACKGROUND: Sepsis is a syndrome with the disturbed host response to severe infection and is a major health problem worldwide. As the front line of infection defense and drug metabolism, the liver is vulnerable to infection- or drug-induced injury. Acute liver injury (ALI) is thus common in patients...

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Detalles Bibliográficos
Autores principales: Cai, Jizhen, Tang, Da, Hao, Xiao, Liu, Enyi, Li, Wenbo, Shi, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310917/
https://www.ncbi.nlm.nih.gov/pubmed/37398640
http://dx.doi.org/10.3389/fimmu.2023.1157793