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Glutathione affinity chromatography for the scalable purification of an oncolytic virus immunotherapy from microcarrier cell culture

Therapeutic viral vectors are an emerging technology with several clinical applications in gene therapy, vaccines, and immunotherapy. Increased demand has required the redevelopment of conventional, low-throughput cell culture and purification manufacturing methods such as static cell stacks and ult...

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Detalles Bibliográficos
Autores principales: Swartz, Andrew R., Shieh, Yvonne, Gulasarian, Amanda, Curtis, Erik, Hofmann, Carl F., Baker, Jack B., Templeton, Neil, Olson, Jessica W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310922/
https://www.ncbi.nlm.nih.gov/pubmed/37397964
http://dx.doi.org/10.3389/fbioe.2023.1193454