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Protein post-translational modification by lysine succinylation: Biochemistry, biological implications, and therapeutic opportunities

Lysine succinylation (Ksuc) is a novel protein post-translational modification (PTM) wherein a succinyl group modifies a lysine residue. Ksuc leads to significant chemical and structural changes to the modified protein. Recent studies have shown that Ksuc might play an important role in organism phy...

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Detalles Bibliográficos
Autores principales: Zhao, Guo, Zhen, Junfeng, Liu, Xinyuan, Guo, Jinshuai, Li, Duanduan, Xie, Jianping, Xie, Longxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310984/
https://www.ncbi.nlm.nih.gov/pubmed/37397549
http://dx.doi.org/10.1016/j.gendis.2022.03.009