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Histone post-translational modification and the DNA damage response

DNA is highly vulnerable to spontaneous and environmental timely damage in living cells. DNA damage may cause genetic instability and increase cancer risk if the damages are not repaired timely and efficiently. Human cells possess several DNA damage response (DDR) mechanisms to protect the integrity...

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Detalles Bibliográficos
Autores principales: Song, Haoyun, Shen, Rong, Liu, Xiangwen, Yang, Xuguang, Xie, Kun, Guo, Zhao, Wang, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310986/
https://www.ncbi.nlm.nih.gov/pubmed/37397521
http://dx.doi.org/10.1016/j.gendis.2022.04.002