Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway

More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions. We first found that miR-18a-5p was highly expressed in the bone...

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Detalles Bibliográficos
Autores principales: Zeng, Fanchun, Zhao, Chunrong, Wang, Rujie, Ren, Lingyan, Qiu, Hao, Zou, Zhi, Ding, Haibin, Sun, Zhongyi, Li, Jianmei, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311030/
https://www.ncbi.nlm.nih.gov/pubmed/37397518
http://dx.doi.org/10.1016/j.gendis.2022.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311030/
https://www.ncbi.nlm.nih.gov/pubmed/37397518
http://dx.doi.org/10.1016/j.gendis.2022.06.007

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