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Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis

Progranulin (PGRN) is a multifunctional growth factor involved in many physiological processes and disease states. The apparent protective role of PGRN and the importance of chondrocyte autophagic function in the progression of osteoarthritis (OA) led us to investigate the role of PGRN in the regula...

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Detalles Bibliográficos
Autores principales: Pan, Yiming, Yang, Yuyou, Fan, Mengtian, Chen, Cheng, Jiang, Rong, Liang, Li, Xian, Menglin, Kuang, Biao, Geng, Nana, Feng, Naibo, Deng, Lin, Zheng, Wei, Zhang, Fengmei, Li, Xiaoli, Guo, Fengjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311031/
https://www.ncbi.nlm.nih.gov/pubmed/37397563
http://dx.doi.org/10.1016/j.gendis.2022.05.031