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Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis
Progranulin (PGRN) is a multifunctional growth factor involved in many physiological processes and disease states. The apparent protective role of PGRN and the importance of chondrocyte autophagic function in the progression of osteoarthritis (OA) led us to investigate the role of PGRN in the regula...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311031/ https://www.ncbi.nlm.nih.gov/pubmed/37397563 http://dx.doi.org/10.1016/j.gendis.2022.05.031 |